For the topical field treatment of actinic keratosis (AK) on the face or scalp

Discover
KLISYRI®:

The modern,
5-day
topical treatment
with
minimal downtime

KLISYRI® is an innovative prescription AK treatment
designed with you in mind. You can treat AK
on the face or scalp in just 5 days—with clinically proven
efficacy and safety, plus convenience.

KLISYRI® is an innovative prescription AK treatment
designed with you in mind. You can treat AK on the face
or scalp in just 5 days—with clinically proven
efficacy and safety, plus convenience.

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EFFICACY

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efficacy

SAFETY

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efficacy

CONVENIENCE

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KLISYRI® (tirbanibulin):

AVAILABLE FOR LARGER TREATMENT AREAS

Precise, pre-measured packets eliminate guesswork to help deliver the right dose—every time.

Applying KLISYRI® is easy! Just be sure to keep these tips in mind:

  • Do not use more KLISYRI® than you need to cover the treatment area

  • Using too much KLISYRI®, or using it too often or for too long, can increase your chances of having a severe skin reaction or other side effects

  • Do not get KLISYRI® in, around, or near your eyes, mouth, or lips

  • Do not touch your eyes while you are applying KLISYRI®

Please see additional information in the
How should I use KLISYRI®? section below
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Meet Kaitlyn,
a busy professional with AK, and hear why she needs a treatment that works for her AK and her lifestyle needs. Tap to see more.

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SAVINGS & SUPPORT

Options to make treatment affordable

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Pay as little as $25 for your prescription through Almirall AdvantageII

If you have commercial (non-government) coverage, you may be able to pay as little as $25 for your KLISYRI® prescription.

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Access the KLISYRI® co-pay card

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Also available through GoodRx®

For patients without (or who opt not to use) commercial insurance, GoodRx® provides an additional option for savings.

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Save up to 80% with GoodRx®#

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IIEligible patients with commercial (non-government) insurance only. Terms and conditions apply. Current as of April 3, 2023. Coverage is subject to change. Patients may pay as little as $25 if covered by insurance and $95 if not covered.

GoodRx® is not insurance but may be used instead of insurance.

#Prices may vary at different pharmacies. Check goodrx.com for the most current pricing information near you.

Save with the KLISYRI® comprehensive specialty pharmacy network

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When you use an Almirall in-network pharmacy, you can access your prescription for the lowest copay possible ($25 if covered by insurance, $95 if not covered) and your prescription can be shipped directly to you.

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Find a pharmacy

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Designed to support your treatment needs

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Download helpful information about AK and treatment with KLISYRI®, including how to apply.

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Download patient brochure

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IMPORTANT SAFETY INFORMATION

Important: KLISYRI is for use on the skin only (topical). Do not use KLISYRI in, around, or near your eyes, mouth or lips.

What is KLISYRI?

KLISYRI is a prescription medicine used on the skin to treat actinic keratosis on the face or scalp. It is not known if KLISYRI is safe and effective in children less than 18 years of age.

Before using KLISYRI, tell your healthcare provider about all of your medical conditions, including if you:

  • are being treated or have been treated for actinic keratosis with any other medicine, procedure, or surgery. You should not use KLISYRI until your skin has healed from other treatments.

  • have other skin problems in the treatment area.

  • are pregnant or plan to become pregnant. It is not known if KLISYRI can harm your unborn baby.

  • are breastfeeding or plan to breastfeed. It is not known if KLISYRI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with KLISYRI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

How should I use KLISYRI?

  • Use KLISYRI as your healthcare provider tells you to. KLISYRI is for skin use only.

  • Apply KLISYRI to evenly cover the treatment area(s) on the face or scalp 1 time a day for 5 days in a row (consecutive) using 1 single dose packet with each application. Do not apply KLISYRI to other areas.

  • Do not use more KLISYRI than you need to cover the treatment area. Using too much KLISYRI, or using it too often, or for too long can increase your chances of having a severe skin reaction or other side effects.

  • Do not cover the treatment area with a dressing after application of KLISYRI. Irritation of the skin may happen if a dressing is applied to the treatment area.

  • Do not get KLISYRI in, around, or near your eyes. Do not touch your eyes while you are applying KLISYRI

    • Wash your hands right away with water and soap after applying KLISYRI. After applying KLISYRI, be careful to keep KLISYRI on the treated area from coming into contact with your eyes. Irritation may happen if you get KLISYRI in your eyes.

    • If you accidentally get KLISYRI in your eyes, flush them with water and get medical care as soon as possible. See, "What are the possible side effects of KLISYRI?"

  • Do not get KLISYRI in, around, or near your mouth or lips.

  • Avoid washing and touching the treated area for approximately 8 hours after application of KLISYRI. After 8 hours, you may wash the area with a mild soap and water.

  • Avoid transferring the product to other areas after application.

  • Throw away any open packet of KLISYRI after use even if there is medicine still left in it.

What are the possible side effects of KLISYRI?

KLISYRI may cause serious side effects, including:

  • Eye irritation can happen if KLISYRI gets into your eyes. If you accidentally get KLISYRI into your eyes, flush them with water and get medical care as soon as possible.

  • Local skin reactions are common but can also be severe during treatment with KLISYRI. Call your healthcare provider if you develop any local skin reactions including redness, flaking or scaling, crusting, or swelling that is more severe, or if you get blisters, peeling, pus, ulcers, or breakdown of your skin.

The most common side effects of KLISYRI include: itching or pain in the treatment area.

These are not all of the possible side effects of KLISYRI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Patient Information and full Prescribing Information.